CTTN Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-65184-60UL
120 ul
£317,00
E-AB-65184-120UL
200 ul
£492,00
E-AB-65184-200UL
Über dieses Produkt
- SKU:
- E-AB-65184
- Zusätzliche Namen:
- CTTN,EMS1,cortactin
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CTTN (NP_612632.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cttn_polyclonal_antibody-e_ab_65184