NUDT15 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-64940-60UL
120 ul
£317,00
E-AB-64940-120UL
200 ul
£492,00
E-AB-64940-200UL
Über dieses Produkt
- SKU:
- E-AB-64940
- Zusätzliche Namen:
- MTH2,NUDT15,NUDT15D
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human NUDT15 (NP_060753.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-nudt15_polyclonal_antibody-e_ab_64940