CASC5 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-64459-60UL
120 ul
£317,00
E-AB-64459-120UL
200 ul
£492,00
E-AB-64459-200UL
Über dieses Produkt
- SKU:
- E-AB-64459
- Zusätzliche Namen:
- AF15Q14,CASC5,CT29,D40,KNL1,MCPH4,PPP1R55,Spc7,hKNL-1,hSpc105
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11,15)(q23,q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CASC5 (NP_733468.3).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-casc5_polyclonal_antibody-e_ab_64459