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Antikörper

GLP1R Polyclonal Antibody

Produktgrößen
60 ul
£235,00
E-AB-62762-60UL
120 ul
£346,00
E-AB-62762-120UL
200 ul
£541,00
E-AB-62762-200UL
Über dieses Produkt
SKU:
E-AB-62762
Zusätzliche Namen:
GLP-1;GLP-1-R;GLP-1R;GLP1R
Anwendung:
Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human GLP1R (NP_002053.3).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody