HDAC5 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-61573-60UL
120 ul
£317,00
E-AB-61573-120UL
200 ul
£492,00
E-AB-61573-200UL
Über dieses Produkt
- SKU:
- E-AB-61573
- Zusätzliche Namen:
- HD5,HDAC5,NY-CO-9
- Anwendung:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human HDAC5 (NP_005465.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hdac5_polyclonal_antibody-e_ab_61573