HLA-DQA1 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-60655-60UL
120 ul
£317,00
E-AB-60655-120UL
200 ul
£492,00
E-AB-60655-200UL
Über dieses Produkt
- SKU:
- E-AB-60655
- Zusätzliche Namen:
- CD,CELIAC1,DQ-A1,GSE,HLA-DQA,HLA-DQA1,class II
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human HLA-DQA1 (NP_002113.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hla_dqa1_polyclonal_antibody-e_ab_60655