(KO Validated) Caspase-3 Polyclonal Antibody
Produktgrößen
60 ul
£254,00
E-AB-60646-60UL
120 ul
£383,00
E-AB-60646-120UL
200 ul
£587,00
E-AB-60646-200UL
Über dieses Produkt
- SKU:
- E-AB-60646
- Zusätzliche Namen:
- Active Caspase 3;CASP3;CPP32;CPP32B;Caspase 3;Caspase-3 p12;SCA-1;active Caspase-3;caspase-3
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human Caspase-3 (NP_004337.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-(ko_validated)_caspase_3_polyclonal_antibody-e_ab_60646