(KO Validated) SMARCA4 Polyclonal Antibody
Produktgrößen
60 ul
£234,00
E-AB-60619-60UL
120 ul
£350,00
E-AB-60619-120UL
200 ul
£533,00
E-AB-60619-200UL
Über dieses Produkt
- SKU:
- E-AB-60619
- Zusätzliche Namen:
- BAF190,BAF190A,BRG1,CSS4,MRD16,RTPS2,SMARCA4,SNF2,SNF2L4,SNF2LB,SWI2,hSNF2b
- Anwendung:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human SMARCA4 (NP_003063.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-(ko_validated)_smarca4_polyclonal_antibody-e_ab_60619