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Antikörper

BMPR1B Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-60551-60UL
120 ul
£317,00
E-AB-60551-120UL
200 ul
£492,00
E-AB-60551-200UL
Über dieses Produkt
SKU:
E-AB-60551
Zusätzliche Namen:
ALK-6,ALK6,AMDD,BDA1D,BDA2,BMPR1B,CDw293
Anwendung:
Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human BMPR1B (NP_001194.1).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody