AIRE Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-60437-60UL
120 ul
£317,00
E-AB-60437-120UL
200 ul
£492,00
E-AB-60437-200UL
Über dieses Produkt
- SKU:
- E-AB-60437
- Zusätzliche Namen:
- AIRE,AIRE1,APECED,APS1,APSI,PGA1
- Anwendung:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human AIRE (NP_000374.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-aire_polyclonal_antibody-e_ab_60437