Factor IX / F9 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-60352-60UL
120 ul
£317,00
E-AB-60352-120UL
200 ul
£492,00
E-AB-60352-200UL
Über dieses Produkt
- SKU:
- E-AB-60352
- Zusätzliche Namen:
- F9,F9 p22,F9p22,FIX,HEMB,P19,PTC,THPH8
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human Factor IX / F9 (NP_000124.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:_f9_polyclonal_antibody-e_ab_60352