ASC / TMS1 Polyclonal Antibody
Produktgrößen
60 ul
£235,00
E-AB-60228-60UL
120 ul
£346,00
E-AB-60228-120UL
200 ul
£541,00
E-AB-60228-200UL
Über dieses Produkt
- SKU:
- E-AB-60228
- Zusätzliche Namen:
- ASC;ASC / TMS1;CARD5;PYCARD;PYD and CARD domain containing;TMS;TMS-1;TMS1
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human ASC / TMS1 (NP_037390.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:_tms1_polyclonal_antibody-e_ab_60228