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Antikörper

TNFR2 Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-60182-60UL
120 ul
£317,00
E-AB-60182-120UL
200 ul
£492,00
E-AB-60182-200UL
Über dieses Produkt
SKU:
E-AB-60182
Zusätzliche Namen:
CD120b,TBPII,TNF Receptor II,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80,TNFRSF1B,p75,p75TNFR
Anwendung:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Host:
Rabbit
Immunogen:
A synthetic peptide of human TNFRSF1B
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody