WISP2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-53562-20UL
60 ul
£183,00
E-AB-53562-60UL
120 ul
£272,00
E-AB-53562-120UL
200 ul
£420,00
E-AB-53562-200UL
Über dieses Produkt
- SKU:
- E-AB-53562
- Zusätzliche Namen:
- CCN family member 5,CCN5,CT58,CTGF L,CTGF-L,Connective tissue growth factor like protein,Connective tissue growth factor related protein 58,Connective tissue growth factor-like protein,Connective tissue growth factor-related protein 58,WISP 2,WISP-2,Wisp2
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human WISP2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-wisp2_polyclonal_antibody-e_ab_53562