WRN Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-53558-20UL
60 ul
£183,00
E-AB-53558-60UL
120 ul
£272,00
E-AB-53558-120UL
200 ul
£420,00
E-AB-53558-200UL
Über dieses Produkt
- SKU:
- E-AB-53558
- Zusätzliche Namen:
- RecQ like type 3,DKFZp686C2056,DNA helicase,Exonuclease WRN,HGNC 12791,OTTHUMP00000225301,RECQL2,RECQL3,RecQ protein-like 2,RecQ-like type 3,RecQ3,Werner,Werner syndrome ATP-dependent helicase,Werner syndrome helicase,Werner syndrome protein
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human WRN
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-wrn_polyclonal_antibody-e_ab_53558