YBX1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-53542-20UL
60 ul
£183,00
E-AB-53542-60UL
120 ul
£272,00
E-AB-53542-120UL
200 ul
£420,00
E-AB-53542-200UL
Über dieses Produkt
- SKU:
- E-AB-53542
- Zusätzliche Namen:
- BP 8,CBF-A,CCAAT binding transcription factor I subunit A,CCAAT-binding transcription factor I subunit A,CSDA2,CSDB,DBPB,DNA binding protein B,DNA-binding protein B,EFI-A,Enhancer factor I subunit A,MDR NF1,MGC104858,MGC110976,MGC117250,NSEP 1,NSEP1,Nucle
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human YBX1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ybx1_polyclonal_antibody-e_ab_53542