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Antikörper

NF1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-53528-20UL
60 ul
£183,00
E-AB-53528-60UL
120 ul
£272,00
E-AB-53528-120UL
200 ul
£420,00
E-AB-53528-200UL
Über dieses Produkt
SKU:
E-AB-53528
Zusätzliche Namen:
DKFZp686J1293,FLJ21220,NF,Neurofibromatosis Noonan syndrome,Neurofibromatosis related protein NF 1,Neurofibromatosis related protein NF1,Neurofibromatosis-related protein NF-1,Neurofibromin 1,Neurofibromin truncated,Neurofibromin1,neurofibromatosis type I
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.7 mg/ml
Weitere Details:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.
Host:
Rabbit
Immunogen:
Synthetic peptide of human NF1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody