HORMAD2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-53135-20UL
60 ul
£183,00
E-AB-53135-60UL
120 ul
£272,00
E-AB-53135-120UL
200 ul
£420,00
E-AB-53135-200UL
Über dieses Produkt
- SKU:
- E-AB-53135
- Zusätzliche Namen:
- 4930529M09Rik;CT46.2;HORM2;HORMA domain containing 2;HORMA domain-containing protein 2;Hormad2;MGC26710;RP23-329P17.4
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.96 mg/ml
- Weitere Details:
- Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human HORMAD2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hormad2_polyclonal_antibody-e_ab_53135