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Antikörper

CD59 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-53030-20UL
60 ul
£183,00
E-AB-53030-60UL
120 ul
£272,00
E-AB-53030-120UL
200 ul
£420,00
E-AB-53030-200UL
Über dieses Produkt
SKU:
E-AB-53030
Zusätzliche Namen:
16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD 59;CD59;CD59 antigen;CD59 antigen complement regulatory protein ;CD59 antigen p18 20;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5;CD_antigen=CD59;EJ16;EJ30;EL32 and
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1.02 mg/ml
Weitere Details:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
Host:
Rabbit
Immunogen:
Fusion protein of human CD59
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody