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Antikörper

IFT57 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-52949-20UL
60 ul
£183,00
E-AB-52949-60UL
120 ul
£272,00
E-AB-52949-120UL
200 ul
£420,00
E-AB-52949-200UL
Über dieses Produkt
SKU:
E-AB-52949
Zusätzliche Namen:
CDNA FLJ10147 fis clone HEMBA1003369,DERP 8,DERP8,Dermal papilla derived protein 8,Dermal papilla-derived protein 8,ESRRBL1 protein,Esrrbl 1,Esrrbl1,Estrogen related receptor beta like 1,Estrogen related receptor beta like protein 1,Estrogen-related recep
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.5 mg/ml
Weitere Details:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
Host:
Rabbit
Immunogen:
Fusion protein of human IFT57
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody