ENSA Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52798-20UL
60 ul
£183,00
E-AB-52798-60UL
120 ul
£272,00
E-AB-52798-120UL
200 ul
£420,00
E-AB-52798-200UL
Über dieses Produkt
- SKU:
- E-AB-52798
- Zusätzliche Namen:
- ARPP 19e ;Alpha endosulfine ;Endosulfine alpha
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.2 mg/ml
- Weitere Details:
- The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human ENSA
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ensa_polyclonal_antibody-e_ab_52798