NGEF Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52771-20UL
60 ul
£183,00
E-AB-52771-60UL
120 ul
£272,00
E-AB-52771-120UL
200 ul
£420,00
E-AB-52771-200UL
Über dieses Produkt
- SKU:
- E-AB-52771
- Zusätzliche Namen:
- neuronal,ARHGEF27,EPHEXIN,Eph receptor-interacting exchange protein,Eph-interacting exchange protein,Ephexin-1,Guanine nucleotide exchange factor,NGEF,Neuronal guanine nucleotide exchange factor,Ngef
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human NGEF
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ngef_polyclonal_antibody-e_ab_52771