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Antikörper

TUBGCP4 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-52657-20UL
60 ul
£183,00
E-AB-52657-60UL
120 ul
£272,00
E-AB-52657-120UL
200 ul
£420,00
E-AB-52657-200UL
Über dieses Produkt
SKU:
E-AB-52657
Zusätzliche Namen:
76P,FLJ14797,GCP 4,GCP4,Gamma tubulin complex component 4,Gamma tubulin ring complex protein,Gamma tubulin ring complex protein (76p gene),Gamma-ring complex protein 76 kDa,Grip76,Hgrip76,TUBGCP 4,TUBGCP4,Tubulin gamma complex associated protei,h76p,hGCP4
Anwendung:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.66 mg/ml
Weitere Details:
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.
Host:
Rabbit
Immunogen:
Fusion protein of human TUBGCP4
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody