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Antikörper

IL6ST Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-52510-20UL
60 ul
£183,00
E-AB-52510-60UL
120 ul
£272,00
E-AB-52510-120UL
200 ul
£420,00
E-AB-52510-200UL
Über dieses Produkt
SKU:
E-AB-52510
Zusätzliche Namen:
CDW;IL6ST;CD130;CDW130;GP130;IL-6RB;Interleukin 6 signal transducer;IR6RB;CD130 antigen;GP130 RAPS;IL 6R beta;IL-6 receptor subunit beta;IL6 ST;IL-6R subunit beta;IL6RB;IL-6R-beta;Interleukin 6 receptor subunit beta;Interleukin receptor beta chain;Interleukin-6 receptor subunit beta;Interleukin-6 signal transducer;Membrane glycoprotein 130;Membrane glycoprotein gp130;Oncostatin M receptor;Oncostatin M receptor alpha subunit;Oncostatin-M receptor subunit alpha
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.7 mg/ml
Weitere Details:
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Host:
Rabbit
Immunogen:
Fusion protein of human IL6ST
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody