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Antikörper

UNC13B Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-52441-20UL
60 ul
£183,00
E-AB-52441-60UL
120 ul
£272,00
E-AB-52441-120UL
200 ul
£420,00
E-AB-52441-200UL
Über dieses Produkt
SKU:
E-AB-52441
Zusätzliche Namen:
MGC133279,MGC133280,Munc13-2,Protein unc-13 homolog B,UN13B,UNC13,Unc13b,Unc13h2,hmunc13,munc13,unc-13 homolog B (C. elegans)
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.5 mg/ml
Weitere Details:
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Host:
Rabbit
Immunogen:
Fusion protein of human UNC13B
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody