ZNF354A Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52385-20UL
60 ul
£183,00
E-AB-52385-60UL
120 ul
£272,00
E-AB-52385-120UL
200 ul
£420,00
E-AB-52385-200UL
Über dieses Produkt
- SKU:
- E-AB-52385
- Zusätzliche Namen:
- and developmentally regulated protein 1, ischemia,EZNF,HKL1,HLK1,Homo sapiens zinc finger protein 354A,KID 1,KID1,Kidney,Renal transcription factor Kid 1 ,TCF-17,TCF17,Transcription factor 17,Z354A,ZNF354,Zinc finger protein 354A,Zinc finger protein eZNF
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krueppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human ZNF354A
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-znf354a_polyclonal_antibody-e_ab_52385