ALKBH8 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52350-20UL
60 ul
£183,00
E-AB-52350-60UL
120 ul
£272,00
E-AB-52350-120UL
200 ul
£420,00
E-AB-52350-200UL
Über dieses Produkt
- SKU:
- E-AB-52350
- Zusätzliche Namen:
- 4930562C03Rik;8030431D03Rik;9430088N01Rik;ABH8;ALKB8;ALKBH8;AlkB homologue 8;Alkylated DNA repair protein alkB homolog 8;FLJ38204;MGC10235;OTTHUMP00000211286;OTTHUMP00000211287;Pr;alkB alkylation repair homolog 8;alkB alkylation repair homolog 8 (E. coli)
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-alkbh8_polyclonal_antibody-e_ab_52350