EDARADD Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52310-20UL
60 ul
£183,00
E-AB-52310-60UL
120 ul
£272,00
E-AB-52310-120UL
200 ul
£420,00
E-AB-52310-200UL
Über dieses Produkt
- SKU:
- E-AB-52310
- Zusätzliche Namen:
- Cr;Crinkled homolog;ED3;EDA3;EDAD;EDAR associated death domain;EDAR-associated death domain protein;EDARADD;Ectodysplasin-A receptor-associated adapter protein;Protein crinkled homolog;ectodysplasia A receptor associated death domain
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.9 mg/ml
- Weitere Details:
- This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-edaradd_polyclonal_antibody-e_ab_52310