CDK4 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-52141-20UL
60 ul
£183,00
E-AB-52141-60UL
120 ul
£272,00
E-AB-52141-120UL
200 ul
£420,00
E-AB-52141-200UL
Über dieses Produkt
- SKU:
- E-AB-52141
- Zusätzliche Namen:
- CDK4;CDK4 protein;CMM 3;CMM3;Cdk 4;Cell division kinase 4;Cell division protein kinase 4;Crk3;Cyclin dependent kinase 4;Cyclin-dependent kinase 4;MGC14458;Melanoma cutaneous malignant 3;PSK J3;PSK-J3;cdk4;p34 cdk4
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.02 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CDK4
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cdk4_polyclonal_antibody-e_ab_52141