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Antikörper

NFKB1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-52131-20UL
60 ul
£183,00
E-AB-52131-60UL
120 ul
£272,00
E-AB-52131-120UL
200 ul
£420,00
E-AB-52131-200UL
Über dieses Produkt
SKU:
E-AB-52131
Zusätzliche Namen:
DKFZp686C01211,DNA binding factor KBF1,DNA binding factor KBF1 EBP1,DNA-binding factor KBF1,EBP 1,EBP-1,EBP1,KBF1,MGC54151,NF kB1,NF kappa B,NF kappaB,NF kappabeta,NFKB 1,NFKB p105,NFKB p50,NFKB1,NFkappaB,Nfkb1,Nuclear factor kappa B DNA binding subu,nf b
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.38 mg/ml
Weitere Details:
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Fusion protein of human NFKB1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody