Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-51039-20UL
60 ul
£183,00
E-AB-51039-60UL
120 ul
£272,00
E-AB-51039-120UL
200 ul
£420,00
E-AB-51039-200UL
Über dieses Produkt
- SKU:
- E-AB-51039
- Zusätzliche Namen:
- ERK-1,ERK1,ERT2,Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 3,MAP kinase isoform p44,MAPK 3,MAPK3,Microtubule-associated protein 2 kinase,Mitogen-activated protein kinase 3,PRKM3,p,p44-MAPK
- Anwendung:
- IHC-Paraffin, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 4D4
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
- Host:
- Mouse
- Immunogen:
- Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
- Isotyp:
- IgG
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:205)_monoclonal_antibody-e_ab_51039