CXCL12/SDF1 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
E-AB-40578-25UL
100 ul
£291,00
E-AB-40578-100UL
Über dieses Produkt
- SKU:
- E-AB-40578
- Zusätzliche Namen:
- SDF-1;Cxcl12
- Anwendung:
- Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12A Alpha and SDF1/CXCL12B Beta) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat CXCL12 protein expressed by E.coli.
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:sdf1_polyclonal_antibody-e_ab_40578