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Antikörper

PERK Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-32546-20UL
60 ul
£183,00
E-AB-32546-60UL
120 ul
£272,00
E-AB-32546-120UL
200 ul
£420,00
E-AB-32546-200UL
Über dieses Produkt
SKU:
E-AB-32546
Zusätzliche Namen:
DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,HRI,Heme regulated EIF2 alpha kinase,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinas
Anwendung:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the N-terminal region of human PERK
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody