FAK Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-31399-20UL
60 ul
£183,00
E-AB-31399-60UL
120 ul
£272,00
E-AB-31399-120UL
200 ul
£420,00
E-AB-31399-200UL
Über dieses Produkt
- SKU:
- E-AB-31399
- Zusätzliche Namen:
- FADK;FADK 1;FAK related non kinase polypeptide;FAK1;FRNK;Focal adhesion Kinase;Focal adhesion kinase 1;Focal adhesion kinase isoform FAK Del33;Focal adhesion kinase related nonkinase;PPP1R71;Protein phosphatase 1 regulatory subunit 7;p125FAK;pp125FAK
- Anwendung:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human FAK around the non-phosphorylation site of Tyr397.
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-fak_polyclonal_antibody-e_ab_31399