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Antikörper

E-Cadherin Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-31261-20UL
60 ul
£183,00
E-AB-31261-60UL
120 ul
£272,00
E-AB-31261-120UL
200 ul
£420,00
E-AB-31261-200UL
Über dieses Produkt
SKU:
E-AB-31261
Zusätzliche Namen:
Arc 1;CADH1;CAM 120/80;CD 324;CD324;CD324 antigen;CDHE;Cadherin 1;Cadherin1;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin;cadherin 1 type 1 E-cadherin;cdh1;epithelial calcium dependant adhesion protein
Anwendung:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the N-terminal region of human E-cadherin
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody