BCL-x Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-30640-20UL
60 ul
£183,00
E-AB-30640-60UL
120 ul
£272,00
E-AB-30640-120UL
200 ul
£420,00
E-AB-30640-200UL
Über dieses Produkt
- SKU:
- E-AB-30640
- Zusätzliche Namen:
- Apoptosis regulator Bcl X;Apoptosis regulator Bcl-X;Apoptosis regulator BclX;B cell lymphoma 2 like;B2CL1;BCL XL/S;BCL2L;BCLX;Bcl 2 like 1 protein;Bcl X;Bcl xL;Bcl xS;Bcl-2-like protein 1;Bcl2 Like 1;Bcl2 related gene;Bcl2-L-1;Bcl2l1;BclXL;BclXs;DKFZp781P
- Anwendung:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of Thr47.
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-bcl_x_polyclonal_antibody-e_ab_30640