MAP2K2 Monoclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-22162-20UL
60 ul
£183,00
E-AB-22162-60UL
120 ul
£272,00
E-AB-22162-120UL
200 ul
£420,00
E-AB-22162-200UL
Über dieses Produkt
- SKU:
- E-AB-22162
- Zusätzliche Namen:
- CFC syndrome,CFC4,Cardiofaciocutaneous syndrome,Dual specificity mitogen activated protein kinase kinase 2,Dual specificity mitogen-activated protein kinase kinase 2,ERK activator kinase 2,FLJ26075,MAP kinase kinase 2,MAPK / ERK kinase 2,MAPK/ERK k,map2k2
- Anwendung:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 2C3
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
- Host:
- Mouse
- Immunogen:
- Synthesized peptide derived from human MEK-2 around the non-phosphorylation site of T394.
- Isotyp:
- IgG
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-map2k2_monoclonal_antibody-e_ab_22162