NBR1 Monoclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-22148-20UL
60 ul
£183,00
E-AB-22148-60UL
120 ul
£272,00
E-AB-22148-120UL
200 ul
£420,00
E-AB-22148-200UL
Über dieses Produkt
- SKU:
- E-AB-22148
- Zusätzliche Namen:
- 1A1 3B,1A13B,B box protein,Cell migration-inducing gene 19 protein,KIAA0049,M17S2,MIG 19,MIG19,Membrane component,Membrane component chromosome 17 surface marker 2,Migration inducing protein,chromosome 17,surface marker 2 (ovarian carcinoma antigen CA125)
- Anwendung:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 4C6
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
- Host:
- Mouse
- Immunogen:
- Recombinant Protein of NBR1
- Isotyp:
- IgG
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-nbr1_monoclonal_antibody-e_ab_22148