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Antikörper

BECN1 Monoclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-22139-20UL
60 ul
£183,00
E-AB-22139-60UL
120 ul
£272,00
E-AB-22139-120UL
200 ul
£420,00
E-AB-22139-200UL
Über dieses Produkt
SKU:
E-AB-22139
Zusätzliche Namen:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;BECN 1;BECN1;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;Becn1;C;Coiled coil myosin like BCL2 interacting protein
Anwendung:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
3C6
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Host:
Mouse
Immunogen:
Synthetic Peptide of Beclin-1
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody