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Antikörper

Active CASP3 Monoclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-22115-20UL
60 ul
£183,00
E-AB-22115-60UL
120 ul
£272,00
E-AB-22115-120UL
200 ul
£420,00
E-AB-22115-200UL
Über dieses Produkt
SKU:
E-AB-22115
Zusätzliche Namen:
A830040C14Rik;Apopain;CASP-3;CASP3;CC3;CPP-32;CPP32;CPP32B;Casp3a;Caspase 3;Caspase-3 subunit p12;Cysteine p;apoptosis-related cysteine peptidase;apoptosis-related cysteine protease;apoptosis-related cysteine protease a
Anwendung:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
5A2
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Host:
Mouse
Immunogen:
Recombinant Protein
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody