Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-21121-20UL
60 ul
£183,00
E-AB-21121-60UL
120 ul
£272,00
E-AB-21121-120UL
200 ul
£420,00
E-AB-21121-200UL
Über dieses Produkt
- SKU:
- E-AB-21121
- Zusätzliche Namen:
- 5'-AMP-activated protein kinase catalytic subunit alpha-1,ACACA kinase,AMPK,AMPK subunit alpha-1,AMPK1,Acetyl-CoA carboxylase kinase,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA1,PRKAA2,Tau-protein kinase PRKAA1
- Anwendung:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic A Alpha subunit and regulatory B Beta and G Gamma subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human AMPKA Alpha1/2 around the phosphorylation site of Thr183/172
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Non-human Primate, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:172)_polyclonal_antibody-e_ab_21121