Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-20966-20UL
60 ul
£183,00
E-AB-20966-60UL
120 ul
£272,00
E-AB-20966-120UL
200 ul
£420,00
E-AB-20966-200UL
Über dieses Produkt
- SKU:
- E-AB-20966
- Zusätzliche Namen:
- GRB1,P85A,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,p85,p85 alpha,polypeptide 1 (p85 alpha),regulatory subunit
- Anwendung:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human PI 3-kinase p85/p55 around the phosphorylation site of Tyr467/199
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Non-human Primate, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:199)_polyclonal_antibody-e_ab_20966