PCDHGB5 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19758-20UL
60 ul
£183,00
E-AB-19758-60UL
120 ul
£272,00
E-AB-19758-120UL
200 ul
£420,00
E-AB-19758-200UL
Über dieses Produkt
- SKU:
- E-AB-19758
- Zusätzliche Namen:
- PCDH gamma B5,PCDH-GAMMA-B5,PCDHGB 5,Protocadherin gamma B5,Protocadherin gamma subfamily B 5
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1.4 mg/ml
- Weitere Details:
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human PCDHGB5
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-pcdhgb5_polyclonal_antibody-e_ab_19758