CEND1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19691-20UL
60 ul
£183,00
E-AB-19691-60UL
120 ul
£272,00
E-AB-19691-120UL
200 ul
£420,00
E-AB-19691-200UL
Über dieses Produkt
- SKU:
- E-AB-19691
- Zusätzliche Namen:
- BM88 ;BM88 antigen;Cell cycle exit and neuronal differentiation 1 ;Cell cycle exit and neuronal differentiation protein 1;FLJ90066;MGC34326
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.9 mg/ml
- Weitere Details:
- BM88, also known as CEND1 (cell cycle exit and neuronal differentiation protein 1), is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CEND1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cend1_polyclonal_antibody-e_ab_19691