ATM Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19625-20UL
60 ul
£183,00
E-AB-19625-60UL
120 ul
£272,00
E-AB-19625-120UL
200 ul
£420,00
E-AB-19625-200UL
Über dieses Produkt
- SKU:
- E-AB-19625
- Zusätzliche Namen:
- A-T mutated;A-T mutated homolog;AT mutated;AT1;ATA;ATC;ATD;ATDC;ATE;ATM;ATM serine/threonine kinase;Ataxia telangiectasia mutated;Ataxia telangiectasia mutated gene;Ataxia telangiectasia mutated homolog;Ataxia telangiectasia mutated homolog (human);DK
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.2 mg/ml
- Weitere Details:
- The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ATM
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-atm_polyclonal_antibody-e_ab_19625