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Antikörper

HUWE1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-19540-20UL
60 ul
£183,00
E-AB-19540-60UL
120 ul
£272,00
E-AB-19540-120UL
200 ul
£420,00
E-AB-19540-200UL
Über dieses Produkt
SKU:
E-AB-19540
Zusätzliche Namen:
ARF BP1;ARF binding protein 1;ARF-BP1;ARF-binding protein 1;BJ-HCC-24 tumor antigen;E3 ubiquitin protein ligase HUWE1;E3 ubiquitin-protein ligase HUWE1;HECT;HECT UBA and WWE domain containing protein 1;HECT domain protein LASU1;HectH9;Homologous to E6AP c
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.8 mg/ml
Weitere Details:
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Host:
Rabbit
Immunogen:
Synthetic peptide of human HUWE1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody