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Antikörper

DPPA4 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-19445-20UL
60 ul
£183,00
E-AB-19445-60UL
120 ul
£272,00
E-AB-19445-120UL
200 ul
£420,00
E-AB-19445-200UL
Über dieses Produkt
SKU:
E-AB-19445
Zusätzliche Namen:
2410091M23Rik;DPPA4;Developmental pluripotency associated 4;Developmental pluripotency associated protein 4;Developmental pluripotency-associated protein 4;Dppa 4;FLJ10713
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1.56 mg/ml
Weitere Details:
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of human DPPA4
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody