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Antikörper

PEG3 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-19429-20UL
60 ul
£183,00
E-AB-19429-60UL
120 ul
£272,00
E-AB-19429-120UL
200 ul
£420,00
E-AB-19429-200UL
Über dieses Produkt
SKU:
E-AB-19429
Zusätzliche Namen:
KIAA0287,PEG3,Paternally-expressed gene 3 protein,ZSCAN24,Zinc finger and SCAN domain-containing protein 24
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.8 mg/ml
Weitere Details:
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
Host:
Rabbit
Immunogen:
Synthetic peptide of human PEG3
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody