HIPK3 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19326-20UL
60 ul
£183,00
E-AB-19326-60UL
120 ul
£272,00
E-AB-19326-120UL
200 ul
£420,00
E-AB-19326-200UL
Über dieses Produkt
- SKU:
- E-AB-19326
- Zusätzliche Namen:
- ANPK;Androgen receptor interacting nuclear protein kinase;Androgen receptor-interacting nuclear protein kinase;DYRK6;FIST;FIST3;Fas interacting serine/threonine protein kinase;Fas-interacting serine/threonine-protein kinase;HIPK3;Hipk3;homeodomain interac
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HIPK3
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hipk3_polyclonal_antibody-e_ab_19326