CUL4A Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19279-20UL
60 ul
£183,00
E-AB-19279-60UL
120 ul
£272,00
E-AB-19279-120UL
200 ul
£420,00
E-AB-19279-200UL
Über dieses Produkt
- SKU:
- E-AB-19279
- Zusätzliche Namen:
- 2810470J21Rik;AW495282;CUL 4A;CUL-4A;CUL4A;Cul4a;Cul4a protein;Cullin-4A;MGC36573;MGC64071
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.62 mg/ml
- Weitere Details:
- Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83% identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CUL4A
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cul4a_polyclonal_antibody-e_ab_19279